| Tissue Specificity | Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3. |
| Function | S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene. |
| Protein Name | Pr Domain Zinc Finger Protein 2Gata-3-Binding Protein G3bLysine N-Methyltransferase 8Mtb-ZfMte-Binding ProteinPr Domain-Containing Protein 2Retinoblastoma Protein-Interacting Zinc Finger ProteinZinc Finger Protein Riz |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pr Domain Zinc Finger Protein 2 antibodyAnti-Gata-3-Binding Protein G3b antibodyAnti-Lysine N-Methyltransferase 8 antibodyAnti-Mtb-Zf antibodyAnti-Mte-Binding Protein antibodyAnti-Pr Domain-Containing Protein 2 antibodyAnti-Retinoblastoma Protein-Interacting Zinc Finger Protein antibodyAnti-Zinc Finger Protein Riz antibodyAnti-PRDM2 antibodyAnti-KMT8 antibodyAnti-RIZ antibody |
Information sourced from Uniprot.org
