| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Prdm14 |
| Gene ID: | 383491 |
| Uniprot ID: | PRD14_MOUSE |
| Specificity: | Recombinant protein of mouse PRDM14 |
| Tissue Specificity | Restricted to embryonic stem cells and primordial germ cells. Not detected in epiblast-derived stem cells. |
| Function | Transcription factor that has both positive and negative roles on transcription. Plays a role in cellular pluripotency. Essential for germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. Its association with CBFA2T2 is required for the functions in pluripotency and germ cell formation. |
| Protein Name | Pr Domain Zinc Finger Protein 14 Pr Domain-Containing Protein 14 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pr Domain Zinc Finger Protein 14 antibody Anti-Pr Domain-Containing Protein 14 antibody Anti-Prdm14 antibody |
Information sourced from Uniprot.org