| Short Description : | Rabbit polyclonal PPT1 (28-306) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPT1 |
| Gene ID: | 5538 |
| Uniprot ID: | PPT1_HUMAN |
| Immunogen Region: | 28-306 |
| Immunogen Sequence: | DPPAPLPLVIWHGMGDSCCN PLSMGAIKKMVEKKIPGIYV LSLEIGKTLMEDVENSFFLN VNSQVTTVCQALAKDPKLQQ GYNAMGFSQGGQFLRAVAQR CPSPPMINLISVGGQHQGVF GLPRCPGESSHICDFIRKTL NAGAYSKVVQERLVQAEYWH DPIKEDVYRNHSIFLADINQ ERGINESYKKNLMALKKFVM VKFLNDSIVDPVDSEWFGFY RSGQAKETIPLQETSLYTQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-306 of human PPT1 (NP_000301.1). |
| Post Translational Modifications | Glycosylated. |
| Function | Has thioesterase activity against fatty acid thioesters with 14 -18 carbons, including palmitoyl-CoA, S-palmitoyl-N-acetylcysteamine, and palmitoylated proteins. In contrast to PPT2, PPT1 can hydrolyze palmitoylated proteins and palmitoylcysteine. |
| Protein Name | Palmitoyl-Protein Thioesterase 1Ppt-1Palmitoyl-Protein Hydrolase 1 |
| Database Links | Reactome: R-HSA-75105 |
| Cellular Localisation | LysosomeSecretedGolgi ApparatusEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Palmitoyl-Protein Thioesterase 1 antibodyAnti-Ppt-1 antibodyAnti-Palmitoyl-Protein Hydrolase 1 antibodyAnti-PPT1 antibodyAnti-CLN1 antibodyAnti-PPT antibody |
Information sourced from Uniprot.org
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