| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP4R3B |
| Gene ID: | 57223 |
| Uniprot ID: | P4R3B_HUMAN |
| Immunogen Region: | 628-817 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 628-817 of human PPP4R3B (NP_001269779.1). |
| Immunogen Sequence: | YKALESIEYVQTFKGLKTKY EQEKDRQNQKLNSVPSILRS NRFRRDAKALEEDEEMWFNE DEEEEGKAVVAPVEKPKPED DFPDNYEKFMETKKAKESED KENLPKRTSPGGFKFTFSHS ASAANGTNSKSVVAQIPPAT SNGSSSKTTNLPTSVTATKG SLVGLVDYPDDEEEDEEEES SPRKRPRLGS |
| Tissue Specificity | Moderately expressed in tissues and specific brain regions examined. |
| Function | Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. |
| Protein Name | Serine/Threonine-Protein Phosphatase 4 Regulatory Subunit 3bSmek Homolog 2 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeNucleusIn Interphase Localized In The Cytoplasm And (With Higher Levels) The NucleusDuring Metaphase Located In Pericentriolar Regions |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 4 Regulatory Subunit 3b antibodyAnti-Smek Homolog 2 antibodyAnti-PPP4R3B antibodyAnti-KIAA1387 antibodyAnti-PP4R3B antibodyAnti-SMEK2 antibody |
Information sourced from Uniprot.org