• Western blot analysis of extracts of mouse liver, using PPP1R3A antibody (STJ112210) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PPP1R3A antibody (900-1080) (STJ112210)

SKU:
STJ112210

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PPP1R3A (900-1080) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPP1R3A
Gene ID: 5506
Uniprot ID: PPR3A_HUMAN
Immunogen Region: 900-1080
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 900-1080 of human PPP1R3A (NP_002702.2).
Immunogen Sequence: SAFNSDTNRAPQNSSPFSKH HTEISVSTNEQAIAVENAVT TMASQPISTKSENICNSTRE IQGIEKHPYPESKPEEVSRS SGIVTSGSRKERCIGQIFQT EEYSVEKSLGPMILINKPLE NMEEARHENEGLVSSGQSLY TSGEKESDSSASTSLPVEES QAQGNESLFSKYTNSKIPYF L
Tissue Specificity Skeletal muscle and heart.
Post Translational Modifications Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
Function Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
Protein Name Protein Phosphatase 1 Regulatory Subunit 3a
Protein Phosphatase 1 Glycogen-Associated Regulatory Subunit
Protein Phosphatase Type-1 Glycogen Targeting Subunit
Rg1
Cellular Localisation Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Protein Phosphatase 1 Regulatory Subunit 3a antibody
Anti-Protein Phosphatase 1 Glycogen-Associated Regulatory Subunit antibody
Anti-Protein Phosphatase Type-1 Glycogen Targeting Subunit antibody
Anti-Rg1 antibody
Anti-PPP1R3A antibody
Anti-PP1G antibody

Information sourced from Uniprot.org

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