| Host: | Rabbit |
| Applications: | WB/IHC-P/ICC/IF/IP/FC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-PPP1R1A for use in WB, IHC-P, ICC, IF, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R06-9D8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:50FC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | PPP1R1A |
| Gene ID: | 5502 |
| Uniprot ID: | PPR1A_HUMAN |
| Immunogen: | A synthesized peptide derived from human PPP1R1A |
| Post Translational Modifications | Phosphorylation of Thr-35 is required for activity. |
| Function | Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 1aProtein Phosphatase Inhibitor 1I-1Ipp-1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 1a antibodyAnti-Protein Phosphatase Inhibitor 1 antibodyAnti-I-1 antibodyAnti-Ipp-1 antibodyAnti-PPP1R1A antibodyAnti-IPP1 antibody |
Information sourced from Uniprot.org
