| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein phosphatase 1 regulatory subunit 14C (51-100 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R14C |
| Gene ID: | 81706 |
| Uniprot ID: | PP14C_HUMAN |
| Immunogen Region: | 51-100 aa |
| Specificity: | KEPI Polyclonal Antibody detects endogenous levels of KEPI protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PPP1R14C at the amino acid range 51-100 |
| Post Translational Modifications | Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. The main inhibitory site appears to be Thr-73. |
| Function | Inhibitor of the PP1 regulatory subunit PPP1CA. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 14cKinase-Enhanced Pp1 InhibitorPkc-Potentiated Pp1 Inhibitory ProteinSerologically Defined Breast Cancer Antigen Ny-Br-81 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 14c antibodyAnti-Kinase-Enhanced Pp1 Inhibitor antibodyAnti-Pkc-Potentiated Pp1 Inhibitory Protein antibodyAnti-Serologically Defined Breast Cancer Antigen Ny-Br-81 antibodyAnti-PPP1R14C antibodyAnti-KEPI antibody |
Information sourced from Uniprot.org