Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Protein phosphatase 1 regulatory subunit 14C (51-100 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PPP1R14C |
Gene ID: |
81706 |
Uniprot ID: |
PP14C_HUMAN |
Immunogen Region: |
51-100 aa |
Specificity: |
KEPI Polyclonal Antibody detects endogenous levels of KEPI protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human PPP1R14C at the amino acid range 51-100 |
Post Translational Modifications | Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. The main inhibitory site appears to be Thr-73. |
Function | Inhibitor of the PP1 regulatory subunit PPP1CA. |
Protein Name | Protein Phosphatase 1 Regulatory Subunit 14cKinase-Enhanced Pp1 InhibitorPkc-Potentiated Pp1 Inhibitory ProteinSerologically Defined Breast Cancer Antigen Ny-Br-81 |
Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 14c antibodyAnti-Kinase-Enhanced Pp1 Inhibitor antibodyAnti-Pkc-Potentiated Pp1 Inhibitory Protein antibodyAnti-Serologically Defined Breast Cancer Antigen Ny-Br-81 antibodyAnti-PPP1R14C antibodyAnti-KEPI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance