Anti-PPP1R14C antibody (51-100 aa) (STJ93829)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PPP1R14C at the amino acid range 51-100
General Information
| Short Description | Rabbit polyclonal anti-Protein phosphatase 1 regulatory subunit 14C (51-100 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R14C |
| Gene ID | 81706 |
| Uniprot ID | PP14C_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PPP1R14C at the amino acid range 51-100 |
| Immunogen Region | 51-100 aa |
| Specificity | KEPI Polyclonal Antibody detects endogenous levels of KEPI protein. |
Additional Info
| Post Translational Modifications | Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. The main inhibitory site appears to be Thr-73. |
| Function | Inhibitor of the PP1 regulatory subunit PPP1CA. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 14cKinase-Enhanced Pp1 InhibitorPkc-Potentiated Pp1 Inhibitory ProteinSerologically Defined Breast Cancer Antigen Ny-Br-81 |
| Database Links | |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 14c antibodyAnti-Kinase-Enhanced Pp1 Inhibitor antibodyAnti-Pkc-Potentiated Pp1 Inhibitory Protein antibodyAnti-Serologically Defined Breast Cancer Antigen Ny-Br-81 antibodyAnti-PPP1R14C antibodyAnti-KEPI antibody |
Information sourced from Uniprot.org