| Tissue Specificity | Highly expressed in the brain, muscle, heart, and kidney in both fetus and adult. In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas. |
| Function | O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. |
| Protein Name | Protein O-Linked-Mannose Beta-1 -4-N-Acetylglucosaminyltransferase 2Pomgnt2Extracellular O-Linked N-Acetylglucosamine Transferase-LikeGlycosyltransferase-Like Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Linked-Mannose Beta-1 -4-N-Acetylglucosaminyltransferase 2 antibodyAnti-Pomgnt2 antibodyAnti-Extracellular O-Linked N-Acetylglucosamine Transferase-Like antibodyAnti-Glycosyltransferase-Like Domain-Containing Protein 2 antibodyAnti-POMGNT2 antibodyAnti-AGO61 antibodyAnti-C3orf39 antibodyAnti-EOGTL antibodyAnti-GTDC2 antibody |
Information sourced from Uniprot.org
