• Western blot analysis of extracts of various cell lines, using PMPCA antibody (STJ112006) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
  • Western blot analysis of extracts of various cell lines, using PMPCA antibody (STJ112006) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-PMPCA antibody (456-525) (STJ112006)

SKU:
STJ112006

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PMPCA (456-525) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PMPCA
Gene ID: 23203
Uniprot ID: MPPA_HUMAN
Immunogen Region: 456-525
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 456-525 of human PMPCA (NP_055975.1).
Immunogen Sequence: TRSRKLPHELCTLIRNVKPE DVKRVASKMLRGKPAVAALG DLTDLPTYEHIQTALSSKDG RLPRTYRLFR
Tissue Specificity Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis.
Function Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Protein Name Mitochondrial-Processing Peptidase Subunit Alpha
Alpha-Mpp
Inactive Zinc Metalloprotease Alpha
P-55
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-8949664
Cellular Localisation Mitochondrion Matrix
Mitochondrion Inner Membrane
Alternative Antibody Names Anti-Mitochondrial-Processing Peptidase Subunit Alpha antibody
Anti-Alpha-Mpp antibody
Anti-Inactive Zinc Metalloprotease Alpha antibody
Anti-P-55 antibody
Anti-PMPCA antibody
Anti-INPP5E antibody
Anti-KIAA0123 antibody
Anti-MPPA antibody

Information sourced from Uniprot.org

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