| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PMPCA |
| Gene ID: | 23203 |
| Uniprot ID: | MPPA_HUMAN |
| Immunogen Region: | 456-525 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 456-525 of human PMPCA (NP_055975.1). |
| Immunogen Sequence: | TRSRKLPHELCTLIRNVKPE DVKRVASKMLRGKPAVAALG DLTDLPTYEHIQTALSSKDG RLPRTYRLFR |
| Tissue Specificity | Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis. |
| Function | Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. |
| Protein Name | Mitochondrial-Processing Peptidase Subunit AlphaAlpha-MppInactive Zinc Metalloprotease AlphaP-55 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8949664Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Mitochondrial-Processing Peptidase Subunit Alpha antibodyAnti-Alpha-Mpp antibodyAnti-Inactive Zinc Metalloprotease Alpha antibodyAnti-P-55 antibodyAnti-PMPCA antibodyAnti-INPP5E antibodyAnti-KIAA0123 antibodyAnti-MPPA antibody |
Information sourced from Uniprot.org