Anti-PMF1 antibody (1-205) [S4199RM] (STJ11104199)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Polyamine-Modulated Factor 1 (1-205) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4199RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PMF1 |
| Gene ID | 100527963/11243 |
| Uniprot ID | PMF1_HUMAN |
| Immunogen Region | 1-205 |
| Immunogen Sequence | MAEASSANLGSGCEEKRHEG SSSESVPPGTTISRVKLLDT MVDTFLQKLVAAGSYQRFTD CYKCFYQLQPAMTQQIYDKF IAQLQTSIREEISDIKEEGN LEAVLNALDKIVEEGKVRKE PAWRPSGIPEKDLHSVMAPY FLQQRDTLRRHVQKQEAENQ QLADAVLAGRRQVEELQLQV QAQQQAWQALHREQRELVAV LREPE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human PMF1 (NP_009152.2). |
Additional Info
| Tissue Specificity | Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver. |
| Function | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. |
| Protein Name | Polyamine-Modulated Factor 1Pmf-1 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusChromosomeCentromereKinetochoreAssociated With The Kinetochore |
| Alternative Antibody Names | Anti-Polyamine-Modulated Factor 1 antibodyAnti-Pmf-1 antibodyAnti-PMF1 antibody |
Information sourced from Uniprot.org