| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLOD3 |
| Gene ID: |
8985 |
| Uniprot ID: |
PLOD3_HUMAN |
| Specificity: |
This antibody detects endogenous levels of PLOD3 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human PLOD3 |
| Function | Multifunctional enzyme that catalyzes a series of essential post-translational modifications on Lys residues in procollagen. Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. Plays a redundant role in catalyzing the transfer of galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine. Has an essential role by catalyzing the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues. Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues. Essential for normal biosynthesis and secretion of type IV collagens (Probable). Essential for normal formation of basement membranes. |
| Protein Name | Multifunctional Procollagen Lysine Hydroxylase And Glycosyltransferase Lh3 Includes - Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 3Lysyl Hydroxylase 3Lh3 - Procollagen GlycosyltransferaseGalactosylhydroxylysine-GlucosyltransferaseProcollagen GalactosyltransferaseProcollagen Glucosyltransferase |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Rough Endoplasmic ReticulumEndoplasmic Reticulum LumenEndoplasmic Reticulum MembranePeripheral Membrane ProteinLumenal SideSecretedExtracellular SpaceThe Majority Of The Secreted Protein Is Associated With The Extracellular Matrix |
| Alternative Antibody Names | Anti-Multifunctional Procollagen Lysine Hydroxylase And Glycosyltransferase Lh3 Includes - Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 3 antibodyAnti-Lysyl Hydroxylase 3 antibodyAnti-Lh3 - Procollagen Glycosyltransferase antibodyAnti-Galactosylhydroxylysine-Glucosyltransferase antibodyAnti-Procollagen Galactosyltransferase antibodyAnti-Procollagen Glucosyltransferase antibodyAnti-PLOD3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
