Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-Procollagen-Lysine-2-Oxoglutarate 5-Dioxygenase 2 (260-380) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S4678RM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:10000-1:30000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PLOD2 |
Gene ID: |
5352 |
Uniprot ID: |
PLOD2_HUMAN |
Immunogen Region: |
260-380 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 260-380 of human PLOD2/LH2 (NP_000926.2). |
Immunogen Sequence: |
ILLNYFGNYVPNSWTQDNGC TLCEFDTVDLSAVDVHPNVS IGVFIEQPTPFLPRFLDILL TLDYPKEALKLFIHNKEVYH EKDIKVFFDKAKHEIKTIKI VGPEENLSQAEARNMGMDFC R |
Tissue Specificity | Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta. |
Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
Protein Name | Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 2Lysyl Hydroxylase 2Lh2 |
Database Links | Reactome: R-HSA-1650814 |
Cellular Localisation | Rough Endoplasmic Reticulum MembranePeripheral Membrane ProteinLumenal Side |
Alternative Antibody Names | Anti-Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 2 antibodyAnti-Lysyl Hydroxylase 2 antibodyAnti-Lh2 antibodyAnti-PLOD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance