Anti-PLCB2-PLCB2 antibody (C-Term) (STJA0003853)

Name: Anti-PLCB2-PLCB2 antibody (C-Term) (STJA0003853)
SKU: STJA0003853-100
Price: 586.2 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenPeptide corresponding to amino acid residues from the C-terminal region of human PLC Beta 2.

STJA0003853-100

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Short Description	Rabbit polyclonal anti-Phospholipase C B2-PLCB2 (C-Term) for use in IHC in Human and Non-Human Primates samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IHC
Host	Rabbit
Reactivity	Human/Non-Human Primates
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Purification	This antibody was antigen affinity purified from pooled serum.
Dilution Range	IHC 1:1000
Formulation	100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	PLCB2
Gene ID	5330
Uniprot ID	PLCB2_HUMAN
Immunogen	Peptide corresponding to amino acid residues from the C-terminal region of human PLC Beta 2.
Immunogen Region	C-Term

Function	The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting RASGRP4 activation by DAG, to promote neutrophil functional responses.
Protein Name	1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-2 Phosphoinositide Phospholipase C-Beta-2 Phospholipase C-Beta-2 Plc-Beta-2
Database Links	Reactome: R-HSA-112043 Reactome: R-HSA-1855204 Reactome: R-HSA-399997 Reactome: R-HSA-4086398 Reactome: R-HSA-416476 Reactome: R-HSA-418217 Reactome: R-HSA-434316 Reactome: R-HSA-500657 Reactome: R-HSA-9717207
Cellular Localisation
Alternative Antibody Names	Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-2 antibody Anti-Phosphoinositide Phospholipase C-Beta-2 antibody Anti-Phospholipase C-Beta-2 antibody Anti-Plc-Beta-2 antibody Anti-PLCB2 antibody

Information sourced from Uniprot.org