| Host: | Rabbit |
| Applications: | IHC |
| Reactivity: | Human/Non-Human Primates |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospholipase C B2-PLCB2 (C-Term) is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Purification: | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range: | IHC 1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLCB2 |
| Gene ID: | 5330 |
| Uniprot ID: | PLCB2_HUMAN |
| Immunogen Region: | C-Term |
| Immunogen: | Peptide corresponding to amino acid residues from the C-terminal region of human PLC Beta 2. |
| Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting RASGRP4 activation by DAG, to promote neutrophil functional responses. |
| Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-2Phosphoinositide Phospholipase C-Beta-2Phospholipase C-Beta-2Plc-Beta-2 |
| Database Links | Reactome: R-HSA-112043Reactome: R-HSA-1855204Reactome: R-HSA-399997Reactome: R-HSA-4086398Reactome: R-HSA-416476Reactome: R-HSA-418217Reactome: R-HSA-434316Reactome: R-HSA-500657Reactome: R-HSA-9717207 |
| Alternative Antibody Names | Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-2 antibodyAnti-Phosphoinositide Phospholipase C-Beta-2 antibodyAnti-Phospholipase C-Beta-2 antibodyAnti-Plc-Beta-2 antibodyAnti-PLCB2 antibody |
Information sourced from Uniprot.org
