| Function | Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE) which serves as precursor for N-acylethanolamines (NAEs). |
| Protein Name | Phospholipase A And Acyltransferase 1 Hras-Like Suppressor 1Hrsl1Phospholipid-Metabolizing Enzyme A-C1 |
| Database Links | Reactome: R-HSA-1482839 |
| Cellular Localisation | Isoform 1: MembraneSingle-Pass Membrane ProteinCytoplasmIsoform 2: Nucleus |
| Alternative Antibody Names | Anti-Phospholipase A And Acyltransferase 1 antibodyAnti-Hras-Like Suppressor 1 antibodyAnti-Hrsl1 antibodyAnti-Phospholipid-Metabolizing Enzyme A-C1 antibodyAnti-PLAAT1 antibodyAnti-HRASLS antibody |
Information sourced from Uniprot.org
