Anti-PKD1L3 antibody (STJ13101627)

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STJ13101627-100
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Host: Rabbit
Applications: IHC/WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal anti-PKD1L3 for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB. A dilution of 1:1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: Pkd1l3
Gene ID: 244646
Uniprot ID: PK1L3_MOUSE
Specificity: Specific for PKD1L3.
Immunogen: A synthetic peptide from mouse PKD1L3 conjugated to blue carrier protein was used as the antigen.
Post Translational Modifications Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity.
Function Pore-forming subunit of a heterotetrameric, non-selective cation channel that is permeable to Ca(2+). Also shows permeability towards NA(1+), K(+) and Mg(2+). Heterotetrameric complex channel is activated by external low pH and Ca(2+), but opens only when the extracellular pH rises again and after the removal of acid stimulus. May act as a sour taste receptor in gustatory cells.however, its contribution to sour taste perception is unclear in vivo and may be indirect.
Protein Name Polycystin-1-Like Protein 3
Polycystin-1l3
Pc1-Like 3 Protein
Polycystic Kidney Disease Protein 1-Like 3
Database Links
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Interaction With Pkd2l1 Is Required For Localization To The Cell Membrane
Alternative Antibody Names Anti-Polycystin-1-Like Protein 3 antibody
Anti-Polycystin-1l3 antibody
Anti-Pc1-Like 3 Protein antibody
Anti-Polycystic Kidney Disease Protein 1-Like 3 antibody
Anti-Pkd1l3 antibody
Anti-71B10 antibody

Information sourced from Uniprot.org