| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PKD1L2 |
| Gene ID: | 114780 |
| Uniprot ID: | PK1L2_HUMAN |
| Immunogen Region: | 1-306 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human PKD1L2 (NP_001265352.1). |
| Immunogen Sequence: | MGEDSPVAMFSWYLDNTPTE QAEPLLDACRLRGFWPRSLT LLQSNTSTLLLNSSFLQSRG EVIRIRATALTRHAYGEDTY VISTVPPREVPACTIAPEEG TVLTSFAIFCNASTALGPLE FCFCLESGSCLHCGPEPALP SVYLPLGEENNDFVLTVVIS ATNRAGDTQQTQAMAKVALG DTCVEDVAFQAAVSEKIPTA LQGEGGPEQLLQLAKAVSSM LNQEHESQGSGQSLSIDVR |
| Tissue Specificity | Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney. |
| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. |
| Function | May function as an ion-channel regulator. May function as a G-protein-coupled receptor. |
| Protein Name | Polycystin-1-Like Protein 2Polycystin-1l2Pc1-Like 2 ProteinPolycystic Kidney Disease Protein 1-Like 2 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Polycystin-1-Like Protein 2 antibodyAnti-Polycystin-1l2 antibodyAnti-Pc1-Like 2 Protein antibodyAnti-Polycystic Kidney Disease Protein 1-Like 2 antibodyAnti-PKD1L2 antibodyAnti-KIAA1879 antibodyAnti-PC1L2 antibody |
Information sourced from Uniprot.org