STJ70126 staining (2µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-PINX1 antibody (N-Term) (STJ70126)

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STJ70126-100
$431.25
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Short Description :Goat polyclonal antibody anti-PINX1 (N-Term) is suitable for use in ELISA and Western Blot research applications.
Applications:Pep-ELISA/WB
Host:Goat
Reactivity:Human/Mouse/Rat/Pig/Dog/Cow
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.5 mg/mL
Purification:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range:Peptide ELISA: antibody detection limit dilution 1:4000.
WB: Approx 35kDa band seen in Jurkat lysate. Recommended for use at 1-3µg/ml.
Formulation:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction:Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol:PINX1
Gene ID:54984
Uniprot ID:PINX1_HUMAN
Accession Number:NP_060354.4
Immunogen Region:N-Term
Immunogen Sequence:SMLAERRRKQKWAV
Post Translational Modifications Cleaved by enterovirus protease 3C to promote apoptosis.
Function Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.
Protein Name Pin2/Terf1-Interacting Telomerase Inhibitor 1
Liver-Related Putative Tumor Suppressor
Pin2-Interacting Protein X1
Protein 67-11-3
Trf1-Interacting Protein 1
Cellular Localisation Nucleus
Nucleolus
Chromosome
Telomere
Centromere
Kinetochore
Localizes In Nucleoli
At Telomere Speckles And To The Outer Plate Of Kinetochores
Localization To The Kinetochore Is Mediated By Its Central Region And Depends On Ndc80 And Cenpe
Alternative Antibody Names Anti-Pin2/Terf1-Interacting Telomerase Inhibitor 1 antibody
Anti-Liver-Related Putative Tumor Suppressor antibody
Anti-Pin2-Interacting Protein X1 antibody
Anti-Protein 67-11-3 antibody
Anti-Trf1-Interacting Protein 1 antibody
Anti-PINX1 antibody
Anti-LPTL antibody
Anti-LPTS antibody

Information sourced from Uniprot.org

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