Anti-PIGO antibody (950-1050) (STJ11101468)

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STJ11101468
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PIGO
Gene ID: 84720
Uniprot ID: PIGO_HUMAN
Immunogen Region: 950-1050
Specificity: A synthetic peptide corresponding to a sequence within amino acids 950-1050 of human PIGO (NP_116023.2).
Immunogen Sequence: FAVGCPLLLLWPFLCESQGL RKRQQPPGNEADARVRPEEE EEPLMEMRLRDAPQHFYAAL LQLGLKYLFILGIQILACAL AASILRRHLMVWKVFAPKFI F
Function Catalytic subunit of the ethanolamine phosphate transferase 3 complex that transfers an ethanolamine phosphate (EtNP) from a phosphatidylethanolamine (PE) to the 6-OH position of the third alpha-1,2-linked mannose of an alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H6) intermediate to generate a 6-PEtn-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H7) and participates in the tenth step of the glycosylphosphatidylinositol-anchor biosynthesis.
Protein Name Gpi Ethanolamine Phosphate Transferase 3 - Catalytic Subunit
Phosphatidylinositol-Glycan Biosynthesis Class O Protein
Pig-O
Hgpcr43
Database Links Reactome: R-HSA-162710
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Gpi Ethanolamine Phosphate Transferase 3 - Catalytic Subunit antibody
Anti-Phosphatidylinositol-Glycan Biosynthesis Class O Protein antibody
Anti-Pig-O antibody
Anti-Hgpcr43 antibody
Anti-PIGO antibody
Anti-UNQ632 antibody
Anti-PRO1249 antibody

Information sourced from Uniprot.org