Anti-PIGO antibody (950-1050) (STJ11101468)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PIGO (950-1050) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PIGO |
| Gene ID | 84720 |
| Uniprot ID | PIGO_HUMAN |
| Immunogen Region | 950-1050 |
| Immunogen Sequence | FAVGCPLLLLWPFLCESQGL RKRQQPPGNEADARVRPEEE EEPLMEMRLRDAPQHFYAAL LQLGLKYLFILGIQILACAL AASILRRHLMVWKVFAPKFI F |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 950-1050 of human PIGO (NP_116023.2). |
Additional Info
| Function | Catalytic subunit of the ethanolamine phosphate transferase 3 complex that transfers an ethanolamine phosphate (EtNP) from a phosphatidylethanolamine (PE) to the 6-OH position of the third alpha-1,2-linked mannose of an alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H6) intermediate to generate a 6-PEtn-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H7) and participates in the tenth step of the glycosylphosphatidylinositol-anchor biosynthesis. |
| Protein Name | Gpi Ethanolamine Phosphate Transferase 3 - Catalytic SubunitPhosphatidylinositol-Glycan Biosynthesis Class O ProteinPig-OHgpcr43 |
| Database Links | Reactome: R-HSA-162710 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gpi Ethanolamine Phosphate Transferase 3 - Catalytic Subunit antibodyAnti-Phosphatidylinositol-Glycan Biosynthesis Class O Protein antibodyAnti-Pig-O antibodyAnti-Hgpcr43 antibodyAnti-PIGO antibodyAnti-UNQ632 antibodyAnti-PRO1249 antibody |
Information sourced from Uniprot.org