Immunofluorescence analysis of L929 cells using PIGM Rabbit polyclonal antibody (STJ119837) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.

Anti-PIGM antibody (35-96) (STJ119837)

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STJ119837
€138.13 - €631.88
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/IHC-P/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IHC-P:1:50-1:200
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PIGM
Gene ID: 93183
Uniprot ID: PIGM_HUMAN
Immunogen Region: 35-96
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 35-96 of human PIGM (NP_660150.1).
Immunogen Sequence: YGVFQDRTLHVRYTDIDYQV FTDAARFVTEGRSPYLRATY RYTPLLGWLLTPNIYLSELF GK
Function Catalytic subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis.
Protein Name Gpi Alpha-1 -4-Mannosyltransferase I - Catalytic Subunit
Gpi Mannosyltransferase I
Gpi-Mt-I
Phosphatidylinositol-Glycan Biosynthesis Class M Protein
Pig-M
Database Links Reactome: R-HSA-162710
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Gpi Alpha-1 -4-Mannosyltransferase I - Catalytic Subunit antibody
Anti-Gpi Mannosyltransferase I antibody
Anti-Gpi-Mt-I antibody
Anti-Phosphatidylinositol-Glycan Biosynthesis Class M Protein antibody
Anti-Pig-M antibody
Anti-PIGM antibody

Information sourced from Uniprot.org

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