| Short Description : | Rabbit polyclonal PIGM (35-96) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PIGM |
| Gene ID: | 93183 |
| Uniprot ID: | PIGM_HUMAN |
| Immunogen Region: | 35-96 |
| Immunogen Sequence: | YGVFQDRTLHVRYTDIDYQV FTDAARFVTEGRSPYLRATY RYTPLLGWLLTPNIYLSELF GK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-96 of human PIGM (NP_660150.1). |
| Function | Catalytic subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. |
| Protein Name | Gpi Alpha-1 -4-Mannosyltransferase I - Catalytic SubunitGpi Mannosyltransferase IGpi-Mt-IPhosphatidylinositol-Glycan Biosynthesis Class M ProteinPig-M |
| Database Links | Reactome: R-HSA-162710 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gpi Alpha-1 -4-Mannosyltransferase I - Catalytic Subunit antibodyAnti-Gpi Mannosyltransferase I antibodyAnti-Gpi-Mt-I antibodyAnti-Phosphatidylinositol-Glycan Biosynthesis Class M Protein antibodyAnti-Pig-M antibodyAnti-PIGM antibody |
Information sourced from Uniprot.org
