• STJ70866 (0. 5µg/ml) staining of Mouse Brain Lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • HEK293 overexpressing Human PDE4B (RC211956) and probed with STJ70866 (mock transfection in first lane) , tested by Origene.

Anti-Phosphodiesterase 4B antibody (C-Term) (STJ70866)

SKU:
STJ70866-100

£312.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Phosphodiesterase 4B (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:8000.
WB: Approx 85kDa band observed in Mouse Brain lysates (calculated MW of 83.3kDa according to Human NP_002591.2 and 82.1kDa according to Mouse NP_062814.2). In transfected HEK293 transiently
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PDE4B
Gene ID: 5142
Uniprot ID: PDE4B_HUMAN
Immunogen Region: C-Term
Accession Number: NP_002591.2; NP_001032418.1; NP_001032416.1; NP_001032417.1
Specificity: This antibody is expected to recognise all reported isoforms (NP_002591.2, NP_001032418.1, NP_001032416.1 and NP_001032417.1).
Immunogen Sequence: DIDIATEDKSPVDT
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Protein Name 3' -5'-Cyclic-Amp Phosphodiesterase 4b
Dpde4
Pde32
Camp-Specific Phosphodiesterase 4b
Database Links Reactome: R-HSA-180024 Q07343-3
Cellular Localisation Isoform Pde4b5: Cytoplasm
Cell Membrane
Alternative Antibody Names Anti-3' -5'-Cyclic-Amp Phosphodiesterase 4b antibody
Anti-Dpde4 antibody
Anti-Pde32 antibody
Anti-Camp-Specific Phosphodiesterase 4b antibody
Anti-PDE4B antibody
Anti-DPDE4 antibody

Information sourced from Uniprot.org

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