| Tissue Specificity | Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers. |
| Function | Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. |
| Protein Name | Tyrosine-Protein Kinase Styk1Novel Oncogene With Kinase DomainProtein Pk-UniqueSerine/Threonine/Tyrosine Kinase 1 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Styk1 antibodyAnti-Novel Oncogene With Kinase Domain antibodyAnti-Protein Pk-Unique antibodyAnti-Serine/Threonine/Tyrosine Kinase 1 antibodyAnti-STYK1 antibodyAnti-NOK antibody |
Information sourced from Uniprot.org
