• Western blot analysis of lysates from HeLa cells treated with serum 20% 15', using PTPRA (Phospho-Tyr798) Antibody. The lane on the right is blocked with the phospho peptide.

Anti-Phospho-PTPRA-Tyr798 antibody (753-802 aa) (STJ90477)

SKU:
STJ90477

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse/Rat/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Receptor-type tyrosine-protein phosphatase alpha-Tyr798 (753-802 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTPRA
Gene ID: 5786
Uniprot ID: PTPRA_HUMAN
Immunogen Region: 753-802 aa
Specificity: Phospho-PTP Alpha (Y798) Polyclonal Antibody detects endogenous levels of PTP Alpha protein only when phosphorylated at Y798.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PTPRA around the phosphorylation site of Tyr798 at the amino acid range 753-802
Function Tyrosine protein phosphatase which is involved in integrin-mediated focal adhesion formation. Following integrin engagement, specifically recruits BCAR3, BCAR1 and CRK to focal adhesions thereby promoting SRC-mediated phosphorylation of BRAC1 and the subsequent activation of PAK and small GTPase RAC1 and CDC42.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase Alpha
Protein-Tyrosine Phosphatase Alpha
R-Ptp-Alpha
Database Links Reactome: R-HSA-375165
Reactome: R-HSA-5673001
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Focal Adhesion
Localizes To Focal Adhesion Sites Following Integrin Engagement
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase Alpha antibody
Anti-Protein-Tyrosine Phosphatase Alpha antibody
Anti-R-Ptp-Alpha antibody
Anti-PTPRA antibody
Anti-PTPA antibody
Anti-PTPRL2 antibody

Information sourced from Uniprot.org

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