| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Phospholipase D1-Ser561 (527-576 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLD1 |
| Gene ID: | 5337 |
| Uniprot ID: | PLD1_HUMAN |
| Immunogen Region: | 527-576 aa |
| Specificity: | Phospho-PC-PLD1 (S561) Polyclonal Antibody detects endogenous levels of PC-PLD1 protein only when phosphorylated at S561. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PLD1 around the phosphorylation site of Ser561 at the amino acid range 527-576 |
| Function | Function as phospholipase selective for phosphatidylcholine. Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic. |
| Protein Name | Phospholipase D1Pld 1Hpld1Choline Phosphatase 1Phosphatidylcholine-Hydrolyzing Phospholipase D1 |
| Database Links | Reactome: R-HSA-1483148Reactome: R-HSA-1483166Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013408 |
| Cellular Localisation | CytoplasmPerinuclear RegionEndoplasmic Reticulum MembraneLipid-AnchorCytoplasmic SideGolgi Apparatus MembraneLate Endosome Membrane |
| Alternative Antibody Names | Anti-Phospholipase D1 antibodyAnti-Pld 1 antibodyAnti-Hpld1 antibodyAnti-Choline Phosphatase 1 antibodyAnti-Phosphatidylcholine-Hydrolyzing Phospholipase D1 antibodyAnti-PLD1 antibody |
Information sourced from Uniprot.org
