Anti-Phospho-PLD1-Ser561 antibody (527-576 aa) (STJ91296)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PLD1 around the phosphorylation site of Ser561 at the amino acid range 527-576
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Phospholipase D1-Ser561 (527-576 aa) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLD1 |
| Gene ID | 5337 |
| Uniprot ID | PLD1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PLD1 around the phosphorylation site of Ser561 at the amino acid range 527-576 |
| Immunogen Region | 527-576 aa |
| Specificity | Phospho-PC-PLD1 (S561) Polyclonal Antibody detects endogenous levels of PC-PLD1 protein only when phosphorylated at S561. |
Additional Info
| Function | Function as phospholipase selective for phosphatidylcholine. Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic. |
| Protein Name | Phospholipase D1Pld 1Hpld1Choline Phosphatase 1Phosphatidylcholine-Hydrolyzing Phospholipase D1 |
| Database Links | Reactome: R-HSA-1483148Reactome: R-HSA-1483166Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013408 |
| Cellular Localisation | CytoplasmPerinuclear RegionEndoplasmic Reticulum MembraneLipid-AnchorCytoplasmic SideGolgi Apparatus MembraneLate Endosome Membrane |
| Alternative Antibody Names | Anti-Phospholipase D1 antibodyAnti-Pld 1 antibodyAnti-Hpld1 antibodyAnti-Choline Phosphatase 1 antibodyAnti-Phosphatidylcholine-Hydrolyzing Phospholipase D1 antibodyAnti-PLD1 antibody |
Information sourced from Uniprot.org