| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-PGCA (500-550) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.75 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | NPR1 |
| Gene ID: | 4881 |
| Uniprot ID: | ANPRA_HUMAN |
| Immunogen Region: | 500-550 |
| Immunogen: | Synthetic peptide taken within amino acid region 500-550 on human Atrial natriuretic peptide receptor 1 protein. |
| Post Translational Modifications | Phosphorylation of the protein kinase-like domain is required for full activation by ANP. |
| Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. |
| Protein Name | Atrial Natriuretic Peptide Receptor 1Atrial Natriuretic Peptide Receptor Type AAnp-AAnpr-ANpr-AGuanylate Cyclase AGc-A |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Atrial Natriuretic Peptide Receptor 1 antibodyAnti-Atrial Natriuretic Peptide Receptor Type A antibodyAnti-Anp-A antibodyAnti-Anpr-A antibodyAnti-Npr-A antibodyAnti-Guanylate Cyclase A antibodyAnti-Gc-A antibodyAnti-NPR1 antibodyAnti-ANPRA antibody |
Information sourced from Uniprot.org