Anti-Phospho-MAX-S11 antibody (STJ22282)

Name: Anti-Phospho-MAX-S11 antibody (STJ22282)
SKU: STJ22282
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ22282

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Short Description	Rabbit polyclonal Phospho-MAX-S11 antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	MAX
Gene ID	4149
Uniprot ID	MAX_HUMAN
Immunogen Sequence	VESDE
Specificity	A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3).

Tissue Specificity	High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Post Translational Modifications	Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes.
Function	Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
Protein Name	Protein Max Class D Basic Helix-Loop-Helix Protein 4 Bhlhd4 Myc-Associated Factor X
Database Links	Reactome: R-HSA-1362277 Reactome: R-HSA-69202 Reactome: R-HSA-69656 Reactome: R-HSA-8953750
Cellular Localisation	Nucleus Cell Projection Dendrite
Alternative Antibody Names	Anti-Protein Max antibody Anti-Class D Basic Helix-Loop-Helix Protein 4 antibody Anti-Bhlhd4 antibody Anti-Myc-Associated Factor X antibody Anti-MAX antibody Anti-BHLHD4 antibody

Information sourced from Uniprot.org