• Immunohistochemistry analysis of paraffin-embedded human brain, using SLP-76 (Phospho-Tyr128) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from K562 cells treated with Na3VO4 0.3nM 40', using SLP-76 (Phospho-Tyr128) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of K562 cells using Phospho-SLP-76 (Y128) Polyclonal Antibody

Anti-Phospho-LCP2-Tyr128 antibody (94-143 aa) (STJ90961)

SKU:
STJ90961

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Lymphocyte cytosolic protein 2-Tyr128 (94-143 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LCP2
Gene ID: 3937
Uniprot ID: LCP2_HUMAN
Immunogen Region: 94-143 aa
Specificity: Phospho-SLP-76 (Y128) Polyclonal Antibody detects endogenous levels of SLP-76 protein only when phosphorylated at Y128.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SLP-76 around the phosphorylation site of Tyr128 at the amino acid range 94-143
Post Translational Modifications Phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2. SYK-dependent phosphorylation is required for recruitment of PI3K signaling components.
Function Involved in T-cell antigen receptor mediated signaling.
Protein Name Lymphocyte Cytosolic Protein 2
Sh2 Domain-Containing Leukocyte Protein Of 76 Kda
Slp-76 Tyrosine Phosphoprotein
Slp76
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-202433
Reactome: R-HSA-2424491
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Lymphocyte Cytosolic Protein 2 antibody
Anti-Sh2 Domain-Containing Leukocyte Protein Of 76 Kda antibody
Anti-Slp-76 Tyrosine Phosphoprotein antibody
Anti-Slp76 antibody
Anti-LCP2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance