Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Phospho-Elongation factor 2-Thr56 (31-80 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | EEF2 |
Gene ID: | 1938 |
Uniprot ID: | EF2_HUMAN |
Immunogen Region: | 31-80 aa |
Specificity: | Phospho-EF-2 (T56) Polyclonal Antibody detects endogenous levels of EF-2 protein only when phosphorylated at T56. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human eEF2 around the phosphorylation site of Thr56 at the amino acid range 31-80 |
Function | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. |
Protein Name | Elongation Factor 2 Ef-2 |
Database Links | Reactome: R-HSA-156902 Reactome: R-HSA-5336415 Reactome: R-HSA-5358493 Reactome: R-HSA-6798695 Reactome: R-HSA-8876725 |
Cellular Localisation | Cytoplasm Nucleus Phosphorylation By Csk Promotes Cleavage And Sumoylation-Dependent Nuclear Translocation Of The C-Terminal Cleavage Product |
Alternative Antibody Names | Anti-Elongation Factor 2 antibody Anti-Ef-2 antibody Anti-EEF2 antibody Anti-EF2 antibody |
Information sourced from Uniprot.org