• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using MKP1 (Phospho-Ser359) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-DUSP1-Ser359 antibody (318-367 aa) (STJ91170)

SKU:
STJ91170

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Dual specificity protein phosphatase 1-Ser359 (318-367 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DUSP1
Gene ID: 1843
Uniprot ID: DUS1_HUMAN
Immunogen Region: 318-367 aa
Specificity: Phospho-MKP-1 (S359) Polyclonal Antibody detects endogenous levels of MKP-1 protein only when phosphorylated at S359.
Immunogen: The antiserum was produced against synthesized peptide derived from the human MKP1 around the phosphorylation site of Ser359 at the amino acid range 318-367
Post Translational Modifications Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation.
Function Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Protein Name Dual Specificity Protein Phosphatase 1
Dual Specificity Protein Phosphatase Hvh1
Mitogen-Activated Protein Kinase Phosphatase 1
Map Kinase Phosphatase 1
Mkp-1
Protein-Tyrosine Phosphatase Cl100
Database Links Reactome: R-HSA-112409
Reactome: R-HSA-5675221
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Dual Specificity Protein Phosphatase 1 antibody
Anti-Dual Specificity Protein Phosphatase Hvh1 antibody
Anti-Mitogen-Activated Protein Kinase Phosphatase 1 antibody
Anti-Map Kinase Phosphatase 1 antibody
Anti-Mkp-1 antibody
Anti-Protein-Tyrosine Phosphatase Cl100 antibody
Anti-DUSP1 antibody
Anti-CL100 antibody
Anti-MKP1 antibody
Anti-PTPN10 antibody
Anti-VH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance