Anti-Phospho-CAD-Ser1859 antibody (STJ196260)

SKU:
STJ196260

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human, Mouse, Rat
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Rabbit polyclonal antibody anti-Phospho CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase Ser1859 is suitable for use in Western Blot.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using a specific immunogen.
Concentration: 1 mg/ml
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAD
Gene ID: 790
Uniprot ID: PYR1_HUMAN
Specificity: This antibody detects endogenous levels of Human Mouse Rat CAD (phospho-Ser1859)
Immunogen: Synthesized phosho peptide around human CAD (Ser1859)
Function This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
Protein Name Cad Protein Includes - Glutamine-Dependent Carbamoyl-Phosphate Synthase - Aspartate Carbamoyltransferase - Dihydroorotase
Database Links Reactome: R-HSA-500753
Cellular Localisation Cytoplasm
Nucleus
Cytosolic And Unphosphorylated In Resting Cells
Translocates To The Nucleus In Response To Egf Stimulation
Nuclear Import Promotes Optimal Cell Growth
Alternative Antibody Names Anti-Cad Protein Includes - Glutamine-Dependent Carbamoyl-Phosphate Synthase - Aspartate Carbamoyltransferase - Dihydroorotase antibody
Anti-CAD antibody

Information sourced from Uniprot.org

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