• Western blot analysis of extracts of various cell lines, using PHC1 Antibody (STJ28406) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-PHC1 antibody (750-940) (STJ28406)

SKU:
STJ28406

$151.88 - $705.38
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PHC1 (750-940) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PHC1
Gene ID: 1911
Uniprot ID: PHC1_HUMAN
Immunogen Region: 750-940
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 750-940 of human PHC1 (NP_004417.2).
Immunogen Sequence: FPVGCSQLLKESEKPLQTGL PTGLTENQSGGPLGVDSPSA ELDKKANLLKCEYCGKYAPA EQFRGSKRFCSMTCAKRYNV SCSHQFRLKRKKMKEFQEAN YARVRRRGPRRSSSDIARAK IQGKCHRGQEDSSRGSDNSS YDEALSPTSPGPLSVRAGHG ERDLGNPNTAPPTPELHGIN PVFLSSNPSRW
Function Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones.it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression.
Protein Name Polyhomeotic-Like Protein 1
Hph1
Early Development Regulatory Protein 1
Database Links Reactome: R-HSA-2559580
Reactome: R-HSA-3108214
Reactome: R-HSA-3899300
Reactome: R-HSA-4551638
Reactome: R-HSA-4570464
Reactome: R-HSA-4655427
Reactome: R-HSA-8939243
Reactome: R-HSA-8943724
Reactome: R-HSA-8953750
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Polyhomeotic-Like Protein 1 antibody
Anti-Hph1 antibody
Anti-Early Development Regulatory Protein 1 antibody
Anti-PHC1 antibody
Anti-EDR1 antibody
Anti-PH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance