Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-PERM1 antibody (434-484 aa) (STJ195593)

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STJ195593
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-PGC-1 and ERR-induced regulator in muscle protein 1 (434-484 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PERM1
Gene ID: 84808
Uniprot ID: PERM1_HUMAN
Immunogen Region: 434-484 aa
Specificity: This antibody detects endogenous levels of CA170 at Human/Mouse
Immunogen: Synthesized peptide derived from the human CA170 at the amino acid range 434-484
Function Regulates the expression of selective PPARGC1A/B and ESRRA/B/G target genes with roles in glucose and lipid metabolism, energy transfer, contractile function, muscle mitochondrial biogenesis and oxidative capacity. Required for the efficient induction of MT-CO2, MT-CO3, COX4I1, TFB1M, TFB2M, POLRMT and SIRT3 by PPARGC1A. Positively regulates the PPARGC1A/ESRRG-induced expression of CKMT2, TNNI3 and SLC2A4 and negatively regulates the PPARGC1A/ESRRG-induced expression of PDK4.
Protein Name Pgc-1 And Err-Induced Regulator In Muscle Protein 1
Ppargc1 And Esrr-Induced Regulator In Muscle 1
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 And Estrogen-Related Receptor-Induced Regulator In Muscle 1
Database Links Reactome: R-HSA-2151201
Cellular Localisation Cytoplasm
Nucleus
Shows A Nuclear Localization In The Presence Of Ppargc1a
Alternative Antibody Names Anti-Pgc-1 And Err-Induced Regulator In Muscle Protein 1 antibody
Anti-Ppargc1 And Esrr-Induced Regulator In Muscle 1 antibody
Anti-Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 And Estrogen-Related Receptor-Induced Regulator In Muscle 1 antibody
Anti-PERM1 antibody
Anti-C1orf170 antibody

Information sourced from Uniprot.org

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