| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Proenkephalin-B (201-250 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDYN |
| Gene ID: |
5173 |
| Uniprot ID: |
PDYN_HUMAN |
| Immunogen Region: |
201-250 aa |
| Specificity: |
PDYN Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 201-250 |
| Function | Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin. Leumorphin has a typical opioid activity and may have anti-apoptotic effect. |
| Protein Name | Proenkephalin-BBeta-Neoendorphin-DynorphinPreprodynorphin Cleaved Into - Alpha-Neoendorphin - Beta-Neoendorphin - Big DynorphinBig Dyn - Dynorphin A(1-17Dyn-A17Dynorphin A - Dynorphin A(1-13 - Dynorphin A(1-8 - Leu-Enkephalin - RimorphinDynorphin BDyn-BDynorphin B(1-13 - LeumorphinDynorphin B-29 |
| Database Links | Reactome: R-HSA-111885Reactome: R-HSA-202040Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Proenkephalin-B antibodyAnti-Beta-Neoendorphin-Dynorphin antibodyAnti-Preprodynorphin Cleaved Into - Alpha-Neoendorphin - Beta-Neoendorphin - Big Dynorphin antibodyAnti-Big Dyn - Dynorphin A(1-17 antibodyAnti-Dyn-A17 antibodyAnti-Dynorphin A - Dynorphin A(1-13 - Dynorphin A(1-8 - Leu-Enkephalin - Rimorphin antibodyAnti-Dynorphin B antibodyAnti-Dyn-B antibodyAnti-Dynorphin B(1-13 - Leumorphin antibodyAnti-Dynorphin B-29 antibodyAnti-PDYN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
