Anti-PDE4D7 antibody {FITC} (STJ502342)

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STJ502342-100
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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Chicken/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-PDE4D7 is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: FITC
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.2 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Pde4d
Gene ID: 238871
Uniprot ID: PDE4D_MOUSE
Specificity: Does not crossDoes not cross react with other PDE family members including PDE4A, PDE4B or PDE4C.
Immunogen: Synthetic peptide corresponding to unique amino acid sequence on PDE4D7 variant.
Tissue Specificity Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis.
Post Translational Modifications Sumoylation of long isoforms by PIAS4 augments their activation by PKA phosphorylation and represses their inhibition by ERK phosphorylation.
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Protein Name 3' -5'-Cyclic-Amp Phosphodiesterase 4d
Dpde3
Camp-Specific Phosphodiesterase 4d
Database Links Reactome: R-MMU-180024
Reactome: -MMU-418555
Cellular Localisation Cytoplasm
Membrane
Cytoskeleton
Microtubule Organizing Center
Centrosome
Apical Cell Membrane
Colocalized With Shank2 To The Apical Membrane Of Colonic Crypt Cells
Found In The Soluble Fraction
Associated With Membranes
And Associated With The Cytoskeleton And The Centrosome
Alternative Antibody Names Anti-3' -5'-Cyclic-Amp Phosphodiesterase 4d antibody
Anti-Dpde3 antibody
Anti-Camp-Specific Phosphodiesterase 4d antibody
Anti-Pde4d antibody

Information sourced from Uniprot.org

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