| Short Description : | Rabbit polyclonal PDE1A (446-545) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDE1A |
| Gene ID: | 5136 |
| Uniprot ID: | PDE1A_HUMAN |
| Immunogen Region: | 446-545 |
| Immunogen Sequence: | EASKAETSSYVASSSTTIVG LHIADALRRSNTKGSMSDGS YSPDYSLAAVDLKSFKNNLV DIIQQNKERWKELAAQGESD LHKNSEDLVNAEEKHDETHS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 446-545 of human PDE1A (NP_005010.2). |
| Tissue Specificity | Several tissues, including brain, kidney, testes and heart. |
| Function | Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. |
| Protein Name | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1aCam-Pde 1a61 Kda Cam-PdeHcam-1 |
| Database Links | Reactome: R-HSA-111957Reactome: R-HSA-418457Reactome: R-HSA-418555 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1a antibodyAnti-Cam-Pde 1a antibodyAnti-61 Kda Cam-Pde antibodyAnti-Hcam-1 antibodyAnti-PDE1A antibody |
Information sourced from Uniprot.org
