| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDCD2L |
| Gene ID: | 84306 |
| Uniprot ID: | PDD2L_HUMAN |
| Immunogen Region: | 1-358 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-358 of human PDCD2L (NP_115722.1). |
| Immunogen Sequence: | MAAVLKPVLLGLRDAPVHGS PTGPGAWTASKLGGIPDALP TVAAPRPVCQRCGQPLALVV QVYCPLEGSPFHRLLHVFAC ACPGCSTGGARSWKVFRSQC LQVPEREAQDAQKQGNSLAA EDWCEGADDWGSDTEEGPSP QFTLDFGNDASSAKDVDWTA RLQDLRLQDAVLGAAHPVPP GLPLFLPYYICVADEDDYRD FVNLDHAHSLLRDYQQREGI AMDQLLSQSLPNDGDEKYE |
| Tissue Specificity | Higher expression in lung, colon, mammary gland, cervix, stomach and small intestine. |
| Function | Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase. |
| Protein Name | Programmed Cell Death Protein 2-Like |
| Alternative Antibody Names | Anti-Programmed Cell Death Protein 2-Like antibodyAnti-PDCD2L antibody |
Information sourced from Uniprot.org