Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-PCSK6 antibody (734-784 aa) (STJ193739)

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STJ193739
$64.80 - $340.20
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Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Proprotein convertase subtilisin/kexin type 6 (734-784 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PCSK6
Gene ID: 5046
Uniprot ID: PCSK6_HUMAN
Immunogen Region: 734-784 aa
Specificity: This antibody detects endogenous levels of PCSK6 at Human/Rat
Immunogen: Synthesized peptide derived from the human PCSK6 at the amino acid range 734-784
Function Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXXKRR consensus motif. Likely functions in the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues.
Protein Name Proprotein Convertase Subtilisin/Kexin Type 6
Paired Basic Amino Acid Cleaving Enzyme 4
Subtilisin-Like Proprotein Convertase 4
Spc4
Subtilisin/Kexin-Like Protease Pace4
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-167060
Reactome: R-HSA-6809371
Reactome: R-HSA-8963889
Cellular Localisation Isoform Pace4a-I: Secreted
Isoform Pace4a-Ii: Secreted
Isoform Pace4c: Endoplasmic Reticulum
Not Secreted
Remains Probably In Zymogen Form In Endoplasmic Reticulum
Isoform Pace4cs: Endoplasmic Reticulum
Isoform Pace4e-I: Endomembrane System
Peripheral Membrane Protein
Retained Intracellularly Probably Through A Hydrophobic Cluster In Their C-Terminus
Isoform Pace4e-Ii: Endomembrane System
Isoform Pace4b: Secreted
Alternative Antibody Names Anti-Proprotein Convertase Subtilisin/Kexin Type 6 antibody
Anti-Paired Basic Amino Acid Cleaving Enzyme 4 antibody
Anti-Subtilisin-Like Proprotein Convertase 4 antibody
Anti-Spc4 antibody
Anti-Subtilisin/Kexin-Like Protease Pace4 antibody
Anti-PCSK6 antibody
Anti-PACE4 antibody

Information sourced from Uniprot.org

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