• STJ71170 (0. 5µg/ml) staining of Mouse Eye lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.

Anti-PAX6 antibody (Internal) (STJ71170)

SKU:
STJ71170-100

£303.50
Shipping:
Free Shipping
Current Stock:
Host: Goat
Applications: Pep-ELISA/WB/FC
Reactivity: Human/Mouse/Rat/Fog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-PAX6 (Internal) is suitable for use in ELISA, Western Blot and Flow Cytometry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.3-1µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PAX6
Gene ID: 5080
Uniprot ID: PAX6_HUMAN
Immunogen Region: Internal
Accession Number: NP_000271.1; NP_001595.2
Specificity: This antibody is expected to recognise both reported isoforms (NP_000271.1 and NP_001595.2).
Immunogen Sequence: REEKLRNQRRQASN
Post Translational Modifications Ubiquitinated by TRIM11, leading to ubiquitination and proteasomal degradation.
Function Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Acts as a transcriptional repressor of NFATC1-mediated gene expression.
Protein Name Paired Box Protein Pax-6
Aniridia Type Ii Protein
Oculorhombin
Database Links Reactome: R-HSA-210745
Reactome: R-HSA-381771
Reactome: R-HSA-400511
Reactome: R-HSA-5617472
Cellular Localisation Nucleus
Isoform 1: Nucleus
Isoform 5a: Nucleus
Alternative Antibody Names Anti-Paired Box Protein Pax-6 antibody
Anti-Aniridia Type Ii Protein antibody
Anti-Oculorhombin antibody
Anti-PAX6 antibody
Anti-AN2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance