Anti-PATZ1 antibody (250-350 aa) [SRM5225] (STJ11107107)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal PATZ1 (250-350 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5225 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PATZ1 |
| Gene ID | 23598 |
| Uniprot ID | PATZ1_HUMAN |
| Immunogen Region | 250-350 aa |
| Immunogen Sequence | PFPSVASSAPPLTGKRGRGR PRKANLLDSMFGSPGGLREA GILPCGLCGKVFTDANRLRQ HEAQHGVTSLQLGYIDLPPP RLGENGLPISEDPDGPRKRS R |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human PATZ1 (NP_055138.2). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Transcriptional regulator that plays a role in many biological processes such as embryogenesis, senescence, T-cell development or neurogenesis. Interacts with the TP53 protein to control genes that are important in proliferation and in the DNA-damage response. Mechanistically, the interaction inhibits the DNA binding and transcriptional activity of TP53/p53. Part of the transcriptional network modulating regulatory T-cell development and controls the generation of the regulatory T-cell pool under homeostatic conditions. (Microbial infection) Plays a positive role in viral cDNA synthesis. |
| Protein Name | Poz- - At Hook- - And Zinc Finger-Containing Protein 1Btb/Poz Domain Zinc Finger Transcription FactorProtein Kinase A Ri Subunit Alpha-Associated ProteinZinc Finger And Btb Domain-Containing Protein 19Zinc Finger Protein 278Zinc Finger Sarcoma Gene Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Poz- - At Hook- - And Zinc Finger-Containing Protein 1 antibodyAnti-Btb/Poz Domain Zinc Finger Transcription Factor antibodyAnti-Protein Kinase A Ri Subunit Alpha-Associated Protein antibodyAnti-Zinc Finger And Btb Domain-Containing Protein 19 antibodyAnti-Zinc Finger Protein 278 antibodyAnti-Zinc Finger Sarcoma Gene Protein antibodyAnti-PATZ1 antibodyAnti-PATZ antibodyAnti-RIAZ antibodyAnti-ZBTB19 antibodyAnti-ZNF278 antibodyAnti-ZSG antibody |
Information sourced from Uniprot.org