| Short Description : | Rabbit polyclonal anti-Protein PAT1 homolog 1 (263-313 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PATL1 |
| Gene ID: | 219988 |
| Uniprot ID: | PATL1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human PATL1 at the amino acid range 263-313 |
| Immunogen Region: | 263-313 aa |
| Specificity: | This antibody detects endogenous levels of PATL1 at Human/Mouse/Rat |
| Function | RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. (Microbial infection) In case of infection, required for translation and replication of hepatitis C virus (HCV). |
| Protein Name | Protein Pat1 Homolog 1Pat1-Like Protein 1Protein Pat1 Homolog BPat1bHpat1b |
| Database Links | Reactome: R-HSA-430039 |
| Cellular Localisation | CytoplasmP-BodyNucleusPml BodyNucleus SpecklePredominantly CytoplasmicShuttles Between The Nucleus And The Cytoplasm In A Crm1-Dependent MannerEnriched In Splicing SpecklesLocalization To Nuclear Foci And Speckles Requires Active TranscriptionExcluded From The Nucleolus |
| Alternative Antibody Names | Anti-Protein Pat1 Homolog 1 antibodyAnti-Pat1-Like Protein 1 antibodyAnti-Protein Pat1 Homolog B antibodyAnti-Pat1b antibodyAnti-Hpat1b antibodyAnti-PATL1 antibodyAnti-OK antibodyAnti-KNS-cl.5 antibody |
Information sourced from Uniprot.org
