• STJ71784 (0. 1µg/ml) staining of Human Umbillical Cord lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-Palladin antibody (895-907) (STJ71784)

SKU:
STJ71784-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Palladin (895-907) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.1-0.3µg/ml
ELISA-antibody detection limit dilution 1:2000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PALLD
Gene ID: 23022
Uniprot ID: PALLD_HUMAN
Immunogen Region: 895-907
Accession Number: NP_057165.3
Immunogen Sequence: RDSGDENEPIQER
Post Translational Modifications Phosphorylated predominantly on serines and, to a lesser extent, on tyrosines. Phosphorylation at Ser-1118 by PKB/AKT1 modulates cytoskeletal organization and cell motility.
Function Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci.
Protein Name Palladin
Sih002
Sarcoma Antigen Ny-Sar-77
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Focal Adhesion
Myofibril
Sarcomere
Z Line
Cell Projection
Ruffle
Podosome
Lamellipodium
Axon
Growth Cone
Localizes To Stress Fibers And Z Lines
Preferentially Expressed In The Excitatory Presynaptic Terminals
Alternative Antibody Names Anti-Palladin antibody
Anti-Sih002 antibody
Anti-Sarcoma Antigen Ny-Sar-77 antibody
Anti-PALLD antibody
Anti-KIAA0992 antibody
Anti-CGI-151 antibody

Information sourced from Uniprot.org

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