| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PAICS |
| Gene ID: | 10606 |
| Uniprot ID: | PUR6_HUMAN |
| Immunogen Region: | 176-425 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human PAICS (NP_001072992.1). |
| Immunogen Sequence: | LEKSWLPQNCTLVDMKIEFG VDVTTKEIVLADVIDNDSWR LWPSGDRSQQKDKQSYRDLK EVTPEGLQMVKKNFEWVAER VELLLKSESQCRVVVLMGST SDLGHCEKIKKACGNFGIPC ELRVTSAHKGPDETLRIKAE YEGDGIPTVFVAVAGRSNGL GPVMSGNTAYPVISCPPLTP DWGVQDVWSSLRLPSGLGCS TVLSPEGSAQFAAQIFGLSN HLVWSKLRASILNTWISLK |
| Function | Bifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase catalyzing two reactions of the de novo purine biosynthetic pathway. |
| Protein Name | Bifunctional Phosphoribosylaminoimidazole Carboxylase/Phosphoribosylaminoimidazole Succinocarboxamide SynthetasePaics Includes - Phosphoribosylaminoimidazole CarboxylaseAir CarboxylaseAirc - Phosphoribosylaminoimidazole Succinocarboxamide SynthetaseSaicar Synthetase |
| Database Links | Reactome: R-HSA-73817 |
| Alternative Antibody Names | Anti-Bifunctional Phosphoribosylaminoimidazole Carboxylase/Phosphoribosylaminoimidazole Succinocarboxamide Synthetase antibodyAnti-Paics Includes - Phosphoribosylaminoimidazole Carboxylase antibodyAnti-Air Carboxylase antibodyAnti-Airc - Phosphoribosylaminoimidazole Succinocarboxamide Synthetase antibodyAnti-Saicar Synthetase antibodyAnti-PAICS antibodyAnti-ADE2 antibodyAnti-AIRC antibodyAnti-PAIS antibody |
Information sourced from Uniprot.org