• Immunofluorescence analysis of U2OS cells using PAICS antibody (STJ28533). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using PAICS antibody (STJ28533) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-PAICS antibody (176-425) (STJ28533)

SKU:
STJ28533

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:10-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PAICS
Gene ID: 10606
Uniprot ID: PUR6_HUMAN
Immunogen Region: 176-425
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human PAICS (NP_001072992.1).
Immunogen Sequence: LEKSWLPQNCTLVDMKIEFG VDVTTKEIVLADVIDNDSWR LWPSGDRSQQKDKQSYRDLK EVTPEGLQMVKKNFEWVAER VELLLKSESQCRVVVLMGST SDLGHCEKIKKACGNFGIPC ELRVTSAHKGPDETLRIKAE YEGDGIPTVFVAVAGRSNGL GPVMSGNTAYPVISCPPLTP DWGVQDVWSSLRLPSGLGCS TVLSPEGSAQFAAQIFGLSN HLVWSKLRASILNTWISLK
Function Bifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase catalyzing two reactions of the de novo purine biosynthetic pathway.
Protein Name Bifunctional Phosphoribosylaminoimidazole Carboxylase/Phosphoribosylaminoimidazole Succinocarboxamide Synthetase
Paics Includes - Phosphoribosylaminoimidazole Carboxylase
Air Carboxylase
Airc - Phosphoribosylaminoimidazole Succinocarboxamide Synthetase
Saicar Synthetase
Database Links Reactome: R-HSA-73817
Alternative Antibody Names Anti-Bifunctional Phosphoribosylaminoimidazole Carboxylase/Phosphoribosylaminoimidazole Succinocarboxamide Synthetase antibody
Anti-Paics Includes - Phosphoribosylaminoimidazole Carboxylase antibody
Anti-Air Carboxylase antibody
Anti-Airc - Phosphoribosylaminoimidazole Succinocarboxamide Synthetase antibody
Anti-Saicar Synthetase antibody
Anti-PAICS antibody
Anti-ADE2 antibody
Anti-AIRC antibody
Anti-PAIS antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance