| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PAH |
| Gene ID: | 5053 |
| Uniprot ID: | PH4H_HUMAN |
| Immunogen Region: | 1-290 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human PAH (NP_000268.1). |
| Immunogen Sequence: | MSTAVLENPGLGRKLSDFGQ ETSYIEDNCNQNGAISLIFS LKEEVGALAKVLRLFEENDV NLTHIESRPSRLKKDEYEFF THLDKRSLPALTNIIKILRH DIGATVHELSRDKKKDTVPW FPRTIQELDRFANQILSYGA ELDADHPGFKDPVYRARRKQ FADIAYNYRHGQPIPRVEYM EEEKKTWGTVFKTLKSLYKT HACYEYNHIFPLLEKYCGFH EDNIPQLEDVSQFLQTCTG |
| Post Translational Modifications | Phosphorylation at Ser-16 increases basal activity and facilitates activation by the substrate phenylalanine. |
| Function | Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. |
| Protein Name | Phenylalanine-4-HydroxylasePahPhe-4-Monooxygenase |
| Database Links | Reactome: R-HSA-2160456Reactome: R-HSA-8964208 |
| Alternative Antibody Names | Anti-Phenylalanine-4-Hydroxylase antibodyAnti-Pah antibodyAnti-Phe-4-Monooxygenase antibodyAnti-PAH antibody |
Information sourced from Uniprot.org