![Anti-p57 kip2 antibody [SM5048] (STJA0005048)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180105/403376/STJA0005048_1__72870.1738950441.png?c=1 "Anti-p57 kip2 antibody [SM5048] (STJA0005048)")
![Anti-p57 kip2 antibody [SM5048] (STJA0005048)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180105/403376/STJA0005048_1__72870.1738950441.png?c=1 "Anti-p57 kip2 antibody [SM5048] (STJA0005048)")
| Host: | Mouse |
| Applications: | IHC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-p57 kip2 is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SM5048 |
| Conjugation: | Unconjugated |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC/IF (H) 1:200-1:500 |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | CDKN1C |
| Gene ID: | 1028 |
| Uniprot ID: | CDN1C_HUMAN |
| Immunogen: | Synthesized peptide derived from human p57kip2 |
| Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
| Protein Name | Cyclin-Dependent Kinase Inhibitor 1cCyclin-Dependent Kinase Inhibitor P57P57kip2 |
| Database Links | Reactome: R-HSA-69231Reactome: R-HSA-9661069 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase Inhibitor 1c antibodyAnti-Cyclin-Dependent Kinase Inhibitor P57 antibodyAnti-P57kip2 antibodyAnti-CDKN1C antibodyAnti-KIP2 antibody |
Information sourced from Uniprot.org