| Short Description : | Rabbit polyclonal anti-P2Y purinoceptor 4 (159-208 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | P2RY4 |
| Gene ID: | 5030 |
| Uniprot ID: | P2RY4_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human P2RY4 at the amino acid range 159-208 |
| Immunogen Region: | 159-208 aa |
| Specificity: | P2Y4 Polyclonal Antibody detects endogenous levels of P2Y4 protein. |
| Post Translational Modifications | Phosphorylation of Ser-333 and Ser-334 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium activated kinases. |
| Function | Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. |
| Protein Name | P2y Purinoceptor 4P2y4P2pUridine Nucleotide ReceptorUnr |
| Database Links | Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-P2y Purinoceptor 4 antibodyAnti-P2y4 antibodyAnti-P2p antibodyAnti-Uridine Nucleotide Receptor antibodyAnti-Unr antibodyAnti-P2RY4 antibodyAnti-NRU antibody |
Information sourced from Uniprot.org
