Host: |
Rabbit |
Applications: |
WB/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-P2Y purinoceptor 4 (159-208 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
P2RY4 |
Gene ID: |
5030 |
Uniprot ID: |
P2RY4_HUMAN |
Immunogen Region: |
159-208 aa |
Specificity: |
P2Y4 Polyclonal Antibody detects endogenous levels of P2Y4 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human P2RY4 at the amino acid range 159-208 |
Post Translational Modifications | Phosphorylation of Ser-333 and Ser-334 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium activated kinases. |
Function | Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. |
Protein Name | P2y Purinoceptor 4P2y4P2pUridine Nucleotide ReceptorUnr |
Database Links | Reactome: R-HSA-417957Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-P2y Purinoceptor 4 antibodyAnti-P2y4 antibodyAnti-P2p antibodyAnti-Uridine Nucleotide Receptor antibodyAnti-Unr antibodyAnti-P2RY4 antibodyAnti-NRU antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance